<International Circulation>: What is your opinion about the current best glucose-lowering medicine that can lead to cardiovascular risk reduction?

   《国际循环》：您认为目前最好的能够减少心血管风险的降糖药是哪些？

　 Professor Ray: That’s a tough one because pretty much all of the trials have used complex regimens， they have used more than one drug. If you were to say is there one drug that we have got for which there is the most reliable evidence， it would be metformin. We have that from the UKPDS trial. Beyond that it is much harder to get one particular agent.

      Ray教授:这个问题很难回答，因为几乎所有的试验都是应用综合性的干预手段，应用了一种以上的药物。如果一定要说某一种药物拥有最可靠的循证证据，那就是二甲双胍，UKPDS试验证实了这一点。除此之外，很难再找出另外一种与众不同的药物。